Clomiphene is the most commonly used medication to stimulate ovulation. In medical practice, the drug is used in the treatment of ovarian and endocrine disorders which reduce the chances of becoming pregnant. The high popularity of the drug is largely due to its effectiveness.
What are the chances of conceiving a baby in a woman who uses Clomiphene? What to do if the drug doesn't work? You will find the answers to these questions below.
Anovulatory ovarian dysfunction is considered a common cause of female infertility. Clomiphene mechanism of action can successfully cope with the disorder. Clinical studies have shown that approximately 70% of women suffering from similar disorders in the reproductive system get a mature egg produced from the fallopian tube. At the same time, about a third of patients manage to conceive a child after the first course of treatment with the use of Clomiphene. It is an excellent result given that the chances of getting pregnant in healthy women during ovulation is 30-50%.
The medication also gives a lasting effect in case of inferior luteal phase and anovulation caused by endocrine factors. With rare exceptions, the use of the drug causes ovulation and allows you to get pregnant in about 27% of cases.
The effectiveness of Clomiphene is slightly lower if a woman has a critically low level of gonadotropins. To restore hormonal balance and normalize the functioning of sex glands, several courses of taking the drug may be required.
The lack of results during the first use of Clomiphene shouldn't be a reason for concern or a change in treatment methods. 6 courses of treatment with the use of the drug are allowed in total, and each of them can give the desired effect.
If the start of treatment is unsuccessful, the doctor, as a rule, gradually increases the dosage of the drug. In this case, no more than 750 mg of Clomiphene is allowed to be taken in one course.
In case of serious disorders of the reproductive system, combined treatment is necessary. In such cases, other drugs are prescribed at the same time as Clomiphene. Most often, estrogen-containing drugs or human menopausal gonadotropin are used as an auxiliary medication.